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Study shows baby in the womb reacting to anaesthetic injection

A new study has shown that unborn babies undergoing an anaesthetic injection into their thigh ahead of intrauterine surgery exhibit changes in facial expression similar to newborn babies experiencing pain.

The study, published at the end of last month by a team of researchers in Brazil, ‘Sorting pain out of salience: assessment of pain facial expressions in the human fetus’, found a difference in response between those fetuses exposed to a painful stimulus (an anaesthetic  injection) and those who were not.

Thirteen mothers participated in the study, their babies being between approximately 28 to 34 weeks’ gestation. Five of the babies were known to have a diaphragmatic hernia, whilst the other eight were healthy. These thirteen babies were subsequently divided into three groups: 1) “acute pain group” – these were those five babies with a diaphragmatic hernia who received an anaesthetic injection into their thigh prior to intrauterine surgery; 2) “control group at rest” – the facial expressions of the babies in the womb were recorded during a routine ultrasound; 3) “control group acoustic startle” – the facial expressions of the babies in the womb were recorded during an “acoustic stimulus”.

Fetal facial expressions were recorded before and after stimulus

Using a “high-definition 4-dimensional ultrasound (4D-US)” machine, the facial expressions of the babies in the acute pain group were recorded for “45 seconds before and 45 seconds after the anesthetic injection to the thigh”. In the control group, during a scheduled ultrasound, facial expressions were similarly recorded “after a 5-minute period of rest for the mother, in a quiet and dark room for 45 seconds”. Finally, in the third group “Fetal facial expressions were recorded for 45 seconds before and after the acoustic stimulus”.

The recordings for each group were anonymised and reviewed by “2 blinded researchers who independently scored the facial pictures of each fetus using the Neonatal Facial Coding System” (NFCS) which monitors ten items of facial expression in neonates to evaluate the degree of pain experienced. These items include: brow lowering, eyes squeezed shut, deepening of the nasolabial furrow, open lips, horizontal mouth stretch, vertical mouth stretch, lip purse, taut tongue, tongue protrusion, chin quiver, neck deflection, and yawning. (These last two items were added specifically for this research on the unborn).

Acute pain group participants exhibited an acute pain-related facial response “that may have been experienced as pain”

Each of these items was given 1 point if present and zero if absent. “The product of the screenshot assessment was a single score (between zero and 12) for each fetus.” In the final results, a number of items on the NFCS were removed so that the facial features analysed included: (1) “brow lowering,” (2) “eyes squeezed shut,” (3) “deepening of the nasolabial furrow,” (4) “open lips,” (5) “horizontal mouth stretch,” (6) “vertical mouth stretch,” and the newly added item, (7) “neck deflection”.

Out of these seven features, the study found that “no control fetus scored higher than 4, while in the AP [acute pain] group, no score was less than 5”.

The paper concludes: “our data indicate AP [acute pain] group participants exhibited an acute nociceptive-related [pain-related] facial response, that may have been experienced as pain”.

The paper does acknowledge that “pain cannot be inferred from” facial expression alone. “So, it must [be] pointed out that what was measured in the AP group is not pain per se, but, instead, the acute facial expression responses after a clear noxious stimulus”.

However, the paper also admits that while this is not definitive proof that the baby in the womb, at least at this stage of development, is capable of feeling pain, the “inability to communicate does not negate the possibility that a human […] experiences pain” and that the “acute nociceptive-related [pain-related] facial response […] may have been experienced as pain”.

Increasing evidence of fetal pain

The evidence gathered in this study coheres with the increasing evidence that the unborn can experience pain. Last year, a large number of MPs attended a Parliamentary webinar hosted by the All Party Parliamentary Pro-Life Group (APPPG) to discuss the evidence indicating that the unborn baby may feel pain from as early as 12 weeks’ gestation.

Parliamentarians from across the political spectrum heard from John C Bockmann PA, a U.S. Army physician assistant and member of the Conner Troop Medical Clinic at Fort Drum, New York, and Dr Stuart WG Derbyshire, an Associate Professor in Psychology at the National University of Singapore.

The two recently collaborated on the Journal of Medical Ethics article ‘Reconsidering Fetal Pain’. Though they hold ‘divergent views regarding the morality of abortion’, they approach the issue of fetal pain based on recent scientific and medical developments.

“Good evidence” that the fetus can feel pain from 12 weeks’ gestation

Both Dr Derbyshire and John C Bockmann PA believe there is “good evidence” that the brain and nervous system, which start developing at 12 weeks’ gestation, are sufficient for the baby to feel pain. In their study, they argue that women considering abortion at this stage of pregnancy should be told about the pain their unborn baby could experience while being terminated.

Currently, the use of fetal pain relief in the UK is not required by law or advised in official NICE (National Institute for Health and Care Excellence) or RCOG (Royal College of Obstetricians & Gynaecologists) guidelines.

Right To Life UK spokesperson, Catherine Robinson, said: “There is increasing evidence that many babies in the UK are experiencing pain during abortions”. 

“As this paper is keen to emphasise, the facial expressions seen on the unborn after undergoing an anaesthetic injection into their thigh is not direct proof that pain is experienced. This is in large part due to how pain is defined and the subjective nature of pain – not just for the unborn of course, but for all sentient beings. Nevertheless, the ordinary means by which we detect that another is in pain is through their outward expressions, whether facial, verbal or otherwise. That an unborn child would exhibit similar facial expressions to a neonate when subjected to a similar painful stimulus is indeed yet more powerful evidence of the likely suffering that these unborn children are undergoing”.

“Of course, the likely suffering experienced when receiving an anaesthetic injection is a regrettable necessity given the surgery they are about to undergo. We can only imagine how it is possibly much worse for babies who are given a lethal injection of potassium chloride to their heart in a late-term abortion.This is the same chemical used to execute inmates in the US. The administration of potassium chloride in executions is considered so painful that it is considered necessary to first administer an anaesthetic before its use in state executions.

“In the recordings of these babies, the reaction to the painful stimulus is immediate and obvious. This research is essential to the pro-life movement as it could do so much to help further highlight the humanity of the unborn child”. 

“Right To Life UK recently reported that abortion was the leading cause of death in 2019, with an estimated 73.3 million abortions taking place worldwide. Sadly, this shocking figure does little to move the hearts of abortion supporters. Perhaps, though, clear examples of fetal distress and pain, as seen in this experiment, might do so.  Statistics don’t bleed, but people do, so let’s hope that these images will provide the humanity behind the numbers to prompt the societal change of mind on abortion that we so desperately need”.

Urgent appeal 
to save liveS

Help stop three major anti-life threats.

Help build on the momentum from the defeat of the assisted suicide Bill and make this victory last.

Dear reader,

Thanks to the hard work and dedication of people like you across the UK, after a two-year battle, MPs voted by 286 to 270 to reject the Edwards assisted suicide Bill.

This followed the defeat of the McArthur assisted suicide Bill in Scotland by 69 to 57 in March this year.

Many commentators thought both Bills would become law.

If that had happened, this would have led to the deaths of many thousands of vulnerable people over the coming decades.

Because supporters like you acted, those Bills were stopped.

Because of you, many vulnerable lives have been saved.

A prominent pollster described the campaign against these major attempts to introduce assisted suicide, which brought together people from all walks of life across the UK, as one of the “most successful 21st Century UK social issue campaigns”. You helped make that possible.

WHY WE MUST NOT STOP HERE

What we have achieved together is extraordinary. But we must not rest on our laurels.

Dignity in Dying, a multi-million-pound pressure group, has made clear that it will keep campaigning to legalise assisted suicide. 

We cannot wait until another Bill is brought forward. We need to keep pressing for better care and strengthen the case against legalisation now.

WHAT COMES NEXT

The next phase of our Support Not Suicide campaign will operate across Parliament, media, online and in grassroots communities in every constituency across the United Kingdom.

Our focus now is to build on that momentum from the defeat of these assisted suicide Bills and make these victories last.

We want to build a United Kingdom where assisted suicide is seen as unnecessary – and where legalising it is seen as unthinkable.

The first part of that work is a sustained push for universal access to high-quality palliative, hospice and social care. No one should feel driven towards assisted suicide because they cannot get the care and support they need. 

We have already asked supporters to contact their MPs about improving care. With your help, we will keep that pressure on in every constituency, brief MPs and Peers on gaps in care, and make the case for better provision in the media.

The second part is building on these wins to ensure more MPs and more of the wider public understand the dangers of legalising assisted suicide. We will put evidence of those risks before MPs and Peers. We will work with mainstream journalists to bring the voices of people directly affected, doctors and other experts into the national conversation, and produce clear videos and articles that supporters can share online and in their communities.

Our network of 250,000 supporters covers every constituency in the UK. Thanks to people like you sharing our content, our posts and videos have been viewed more than 100 million times online in the last year. 

We want to utilise that massive reach for this next phase of the campaign.

WE CAN ONLY DO THIS WITH YOUR HELP

The two-year fight to stop these Bills drew heavily on our limited resources.

To replenish those resources and fund the next phase of the Support Not Suicide campaign, we aim to raise at least £199,250 by midnight this Sunday (4 October 2026).

We are, therefore, appealing to you to please give as generously as you can today.

Every donation, large or small, will make a crucial difference in protecting vulnerable lives. Plus, if you are a UK taxpayer, £1 becomes £1.25 with Gift Aid at no extra cost to you.

Will you donate now to help make these victories last and protect vulnerable lives?

Urgent appeal 
to save liveS

Help stop three major anti-life threats.

Help build on the momentum from the defeat of the assisted suicide Bill and make this victory last.