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World’s most premature surviving baby, born at 21 weeks and one day, celebrates fourth birthday

The most premature surviving baby ever, born 132 days early at just 21 weeks and one day, has celebrated his fourth birthday.

Tiny baby Curtis Zy-Keith Means weighed only 14.8 oz (420g) when he was born, and doctors gave him a less than 1% chance of survival.

He was born at the University of Alabama at Birmingham Hospital in Alabama, USA, along with his twin sister C’Aysa, who sadly did not survive. After his unexpected early arrival, Curtis spent nine months in the neonatal intensive care unit at the hospital.

Curtis’s mother Michelle fought for her babies

Brian Sims, a professor of paediatrics in the neonatology division at the University of Alabama Hospital, said “His birth was a complete shock”.

“I was called by my obstetrical colleagues that Curtis’s mom was in the labour and delivery and she was precipitously about to deliver, and they wanted me to go in and talk to her about the poor prognosis of babies being born at 21 weeks and one day”.

“Mom’s question to me was “Can we give my babies a chance?”.

Professor Sims spoke about the chances of survival for babies born so prematurely: “Numbers show that babies born so young have little to no chances of survival”, Sims said. “We typically advise for compassionate care in situations of such extremely preterm births. This allows the parents to hold their babies and cherish what little time they may have together”. 

Despite this, the doctor told Curtis’s mum that they would take their lead from the babies and, if they responded to treatment, they would keep going. 

“It was very stressful”, Michelle said.

Whilst his little sister tragically did not make it, Curtis responded to treatment and showed signs of improvement. 

Dr Colm Travers, assistant professor in the Division of Neonatology at the University of Alabama Birmingham Hospital, said “Initially Curtis was on a lot of breathing support and medications for his heart and lungs to keep him alive and then over the next several weeks we were able to decrease the amount of support and help that we were giving him”.

“Then when he was about three months old we were able to finally take him off the ventilator, and eventually when he was about nine months old we were able to send him home just on a nasal cannula oxygen and also with feeds through a gastrostomy tube”.

Dr Sims said “When Curtis was discharged, there was much excitement in the unit. Curtis was a special young man and there was something unique about him”.

“[Michelle] made the first campaign for Curtis to be alive. She was a champion for her baby, she spoke up for her baby and I’m so thankful that we listened to her”.

Record-breaking boy graduates after 275 days in the hospital

Despite the 1% chance of survival that he was given, after 275 days in hospital, Curtis graduated from the ward and was able to go home. 

“Being able to finally take Curtis home and surprise my older children with their younger brother is a moment I will always remember”, Michelle said. “It was a difficult journey, but I am grateful for the UAB team and their constant support. They took the time to educate me and made sure I knew what was happening every step of the way. They truly cared about my son and me”.

Curtis is now thriving at four years old and holds the Guinness World Record for the youngest-ever premature baby to survive.

Michelle said that Curtis loves playing with his toys and watching Mickey Mouse, which is his favourite cartoon, as well as calling people up on his mother’s phone. He now weighs 33lb (15kg).

Survival rates have improved for extremely premature babies

At 21 weeks and one day, Curtis is the most premature baby ever to survive. 

A 2008 study looking at survival rates for a neonatal intensive care unit in London found that neonatal survival rates at 22 and 23 weeks gestation had improved over time. In 1981-85, no babies who were born at these gestational ages survived to discharge. However, by 1986-90, 19% did and this increased to 54% in the period 1996-2000.

In the decade to 2019 alone, the survival rate for extremely premature babies born at 23 weeks doubled, prompting new guidance from the British Association of Perinatal Medicine (BAPM) that enables doctors to intervene to save premature babies from 22 weeks gestation. The previous clinical guidance, drafted in 2008, set the standard that babies who were born before 23 weeks gestation should not be resuscitated.

Spokesperson for Right To Life UK, Catherine Robinson, said “How amazing to hear that Curtis is doing so well at four years old. The fact that the world’s most premature baby was born only four years ago demonstrates how our medical technologies are improving all the time to provide these very tiny babies with the best chance of survival. What a beautiful outcome for little Curtis and his family”.

Urgent appeal 
to save liveS

Help stop three major anti-life threats.

Only hours left of the appeal to build on the momentum from the defeat of the assisted suicide Bill and make this victory last.

Dear reader,

Thanks to the hard work and dedication of people like you across the UK, after a two-year battle, MPs voted by 286 to 270 to reject the Edwards assisted suicide Bill.

This followed the defeat of the McArthur assisted suicide Bill in Scotland by 69 to 57 in March this year.

Many commentators thought both Bills would become law.

If that had happened, this would have led to the deaths of many thousands of vulnerable people over the coming decades.

Because supporters like you acted, those Bills were stopped.

Because of you, many vulnerable lives have been saved.

A prominent pollster described the campaign against these major attempts to introduce assisted suicide, which brought together people from all walks of life across the UK, as one of the “most successful 21st Century UK social issue campaigns”. You helped make that possible.

WHY WE MUST NOT STOP HERE

What we have achieved together is extraordinary. But we must not rest on our laurels.

Dignity in Dying, a multi-million-pound pressure group, has made clear that it will keep campaigning to legalise assisted suicide. 

We cannot wait until another Bill is brought forward. We need to keep pressing for better care and strengthen the case against legalisation now.

WHAT COMES NEXT

The next phase of our Support Not Suicide campaign will operate across Parliament, media, online and in grassroots communities in every constituency across the United Kingdom.

Our focus now is to build on that momentum from the defeat of these assisted suicide Bills and make these victories last.

We want to build a United Kingdom where assisted suicide is seen as unnecessary – and where legalising it is seen as unthinkable.

The first part of that work is a sustained push for universal access to high-quality palliative, hospice and social care. No one should feel driven towards assisted suicide because they cannot get the care and support they need. 

We have already asked supporters to contact their MPs about improving care. With your help, we will keep that pressure on in every constituency, brief MPs and Peers on gaps in care, and make the case for better provision in the media.

The second part is building on these wins to ensure more MPs and more of the wider public understand the dangers of legalising assisted suicide. We will put evidence of those risks before MPs and Peers. We will work with mainstream journalists to bring the voices of people directly affected, doctors and other experts into the national conversation, and produce clear videos and articles that supporters can share online and in their communities.

Our network of 250,000 supporters covers every constituency in the UK. Thanks to people like you sharing our content, our posts and videos have been viewed more than 100 million times online in the last year. 

We want to utilise that massive reach for this next phase of the campaign.

WE CAN ONLY DO THIS WITH YOUR HELP

The two-year fight to stop these Bills drew heavily on our limited resources.

To replenish those resources and fund the next phase of the Support Not Suicide campaign, we aim to raise at least £199,250 by midnight this Sunday (4 October 2026).

We are, therefore, appealing to you to please give as generously as you can today.

Every donation, large or small, will make a crucial difference in protecting vulnerable lives. Plus, if you are a UK taxpayer, £1 becomes £1.25 with Gift Aid at no extra cost to you.

Will you donate now to help make these victories last and protect vulnerable lives?

Urgent appeal 
to save liveS

Help stop three major anti-life threats.

Only hours left of the appeal to build on the momentum from the defeat of the assisted suicide Bill and make this victory last.