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Paracetamol trial yields promising results for premature babies

A new clinical trial conducted by a hospital in Sydney, Australia may change the way premature babies born with a common heart condition are treated.

Patent ductus arteriosus (PDA), the heart problem in question, is a condition in which excess blood flows to the baby’s lungs at birth, causing breathing difficulties. The condition affects half of infants born at less than 29 weeks gestation.

The trial involved 58 babies aged between 23 and 28 weeks being given paracetamol for five days every six hours from their day of birth.

The trial, which involved dozens of doctors and nurses, was led by neonatologist Tim Schindler at The Royal Hospital for Women in Randwick, Sydney and the results have been published in the peer-reviewed Neonatology Journal. It was carried out over a two-and-a-half-year period from November 2016 to March 2019.

‘Practice-changing’ results 

Dr Schindler told reporters that the results were “practice-changing”.

“If we have a safer alternative, then clinicians are more likely to choose paracetamol than the traditional medications that we’ve used in the past”.

“It’s been quite an exciting result, because the medications that we traditionally have been using are associated with some side effects, some of which are quite serious and paracetamol is potentially safer for these vulnerable babies”.

“The medications we have been using have side effects risking damage to other organs in the body, in particular the kidneys and the gastrointestinal system, even perforating the bowel.

He added, “We didn’t observe any side effects in paracetamol, however larger studies are needed”.

Right To Life UK spokesperson, Catherine Robinson, said: “There are so many wonderful stories of severely premature babies going on to survive, and it is fantastic to see so many advances in our ability to medically treat them so that they are able to live and thrive”.

“Yet with such stories becoming almost commonplace, when will our lawmakers decide to finally re-examine our cruel abortion laws that permit abortion even after the point at which babies are able to survive outside of the womb?”

“Of course, babies who cannot survive outside the womb have the same dignity and worth as the babies that can, and their lives should not be ended either. But the fact that more and more premature babies are going on to survive due to the medical advances discovered by the likes of Dr Schindler is yet more evidence of the cruelty and backward nature of abortion laws in the UK, Australia and beyond”.

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Dear reader,

Thanks to the support from people like you, in 2025, we have grown to 250,000 supporters, reached over 100 million views online, helped bring the Leadbeater assisted suicide Bill within just 12 votes of defeat and fought major proposals to introduce abortion up to birth.

However, the challenges we face are far from over.

FIVE MAJOR BATTLES

In 2026, we will be facing five major battles:

  1. Assisted suicide at Westminster – the Leadbeater Bill
    With this session of the UK Parliament at Westminster expected to continue well into 2026, there are many more months of this battle to fight. There is growing momentum in the House of Lords against the dangerous Leadbeater assisted suicide Bill, but well-funded groups such as Dignity in Dying have poured millions into lobbying, and we must sustain the pressure so this Bill never becomes law.
  2. Assisted suicide in Scotland – the McArthur Bill
    We are expecting to face the final Stage 3 vote on the Scottish McArthur assisted suicide Bill early in the new year. If just seven MSPs switch from voting for to against the Bill, it will be defeated. This is a battle that can be won, but the assisted suicide lobby is working intensely to stop that from happening.
  3. Assisted suicide in Wales – the Senedd vote
    In January, we are expecting the Welsh Senedd to vote on whether they will allow the Leadbeater assisted suicide Bill to be rolled out in Wales. Dignity in Dying and their allies are already putting a big focus on winning this vote. This is going to be another decisive and major battle.
  4. Abortion up to birth at Westminster
    We are going to face major battles over the Antoniazzi abortion up to birth amendment as it moves through the House of Lords. Baroness Monckton has tabled an amendment to overturn this change, and other Peers have proposed changes that would protect more babies from having their lives ended in late-term home abortions.
  5. Abortion up to birth in Scotland
    In Scotland, moves are underway to attempt to introduce an even more extreme abortion law there. An “expert group” undertaking a review of abortion law in Scotland has recommended that the Scottish Government scrap the current 24-week time limit – and abortion be available on social grounds right up to birth. It is expected that the Scottish Government will bring forward final proposals as a Government Bill next year.

If these major threats from our opposition are successful, it would be a disaster. Thousands of lives would be lost.

WE CAN ONLY DEFEAT THESE FIVE MAJOR THREATS WITH YOUR HELP

Work fighting both the abortion and assisted suicide lobbies in 2025 has substantially drained our limited resources.

To cover this gap and ensure we effectively fight these battles in the year ahead, our goal is to raise at least £198,750 by midnight this Sunday, 7 December 2025.

With a number of these battles due to begin within weeks, we need funds in place now so we can move immediately.

£198,750 is the minimum we need; anything extra lets us do even more.

If you are able, please give as generously as you can today. Every donation, large or small, will make a real difference. Plus, if you are a UK taxpayer, Gift Aid adds 25p to every £1 you donate at no extra cost to you.

Will you donate now to help protect vulnerable lives from these five major threats?

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Help fight the five major battles we will face in 2026.